Cantimer's sensing technology platform, illustrated above, consists of a piezo-resistive micro-cantilever embedded in a tiny droplet of an analyte-responsive, sensing polymer. When exposed to the analyte or property for which it has been designed, the physical characteristics of the polymer change (essentially it swells or contracts) deflecting the micro-cantilever upwards or downwards and thereby creating a resistance change in the base that can be detected with simple electronics. The volumetric shift in the polymer may be due to diffusion of the analyte molecule into the polymer, probe target binding on the surface of the polymer or a bulk chemical reaction between the analyte and the sensing material. Since micro-cantilever strains of just a few Angstroms are measurable, sample size can be very small and detection sensitivities of just a few molecules can be achieved. The use of piezo-resistive micro-cantilevers in conjunction with analyte-specific sensing polymers in this manner is a new and basic invention that is covered by Cantimer's intellectual property rights.
The simplicity of Cantimer's approach enables the development of small, portable, rapid-response detection and measurement devices that have virtually no moving parts and are robust, cost effective and easy to use.
In conjunction with its scientific collaborators, Cantimer has demonstrated the potential of its technology platform to be used for the detection and measurement of a broad array of chemical and biological compounds, including viruses, proteins, single strand DNA, electrolytes such as sodium and potassium, biomarkers such as glucose, urea and ethanol and gases such as hydrogen cyanide and carbon monoxide.
Cantimer welcomes enquiries regarding its platform and/or potential new applications. If you are interested in licensing the technology or partnering with Cantimer in the development of sensors or devices for proprietary assays, please contact:
Ray Stewart, Ph.D.
Chief Technology Officer
(650) 566-0800, x302